This delicious Tzatziki Crusted Salmon with Panko is baked to perfection! This Tzatziki Crusted Salmon is perfect for a healthy weeknight dinner and lunch meal prep with the leftovers.
Tzatziki Crusted Salmon with Panko
Let’s talk salmon, in my previous hummus crusted salmon recipe, I mentioned that I am pretty picky when it comes to fish. A lot of times in the past it’s been too fishy for my liking. However, salmon is a great source of omega 3-fatty acid, protein, b vitamin, and potassium so I try to make sure I fit it into my diet.
Baking salmon has been my favourite way of making salmon as It’s just so simple and easy to make and it takes just a few seconds to pop into the oven and have dinner ready after work. It’s hands off and clean up is minimum!
The simple ingredients for this Tzatziki Crusted Salmon with Panko
This tzatziki crusted salmon is literally just salmon and then coat of tzatziki on top and then a panko mix! It’s super simple. As a side, I tossed some diced potatoes with some oil, garlic powder, and pepper and baked until it was golden brown.
This picture shows 1 lb of salmon but I only use half a pound for this recipe. To keep things a little different, I used the other half on my hummus crusted salmon with panko! This way I can “mix and match” the two flavours so I can have a little bit of variety at work.
What to do with the leftovers for this tzatziki crusted salmon
You know that fishy smell in the microwave? Well, that’s what happens when you microwave fish! Whatever I don’t finish for dinner, I pack in my little bento box and take it to work with me the next day. I eat it cold and if I need to microwave my side (if it’s not a leafy salad), I just microwave it separately! Sometimes I break up the cold salmon into pieces to mix in with my salad or I’ll just have it whole. It’s an easy cold work lunch.
Tips for Perfecting this Tzatziki Crusted Salmon with Panko
- squeeze some lemon on this when your done to add an extra layer of flavour to the salmon.
- easily bring it to work the next day with this bento box so you can microwave your side of choice (rice, potatoes, etc) of this dish separately from the salmon.
- if you do not have panko, breadcrumbs can be substituted in but panko is my first choice.
- want to change up the flavour profile? mix some dill and garlic powder into the panko mix.

Tzatziki Crusted Salmon with Panko
Ingredients
- 1/2 lb salmon fillets portioned into 4 pieces
- 5 tbsp tzatziki
- 1/3 cup panko
- 1/5 cup parmesan cheese , skip if you want to cut down on calories
- 1/5 cup butter
- 1 tsp mustard powder
- 1 tbsp honey
Instructions
- Heat your oven (my salmon's instructions states 450F)
- Slice up the salmon and place them on a baking pan (coated with non-sticking spray) and spread a thin layer of tzatziki on each fillet.
- In a small bowl, combine the panko, parmesan cheese, butter, mustard, and honey. Evenly spoon the panko mix onto the tzatziki on top of the salmon fillet.
- Bake for 17 minutes and either serve immediately or eat cold the next day for lunch.
- Optional: while the salmon is baking, you can either prep some carb or salad to go with it. I made roasted potatoes: cut up some potatoes into small pieces, coat with oil, garlic powder, and pepper then baked at the same time as the salmon on a different rack until golden brown.
Nutrition Per Serving
Let’s chat! What is your go-to fast and easy dinner?
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Amanda says
I am ALL over this recipe! :) We often serve tzatziki as a dipping sauce on the side of salmon, and I LOVE that you’ve used it to top the fillets before baking. It must create such a great little creamy layer underneath the crunchy panko. We have salmon once a week usually, so this will definitely be on the menu within the next week!
Sues says
Oh yum, I love this!! I’m always looking for new ways to prepare salmon since I like to make it often and that tzatziki crust looks perfect! I love the little crunch the panko gives the salmon :)
Annemarie says
For a moment I thought using tzatziki to coat salmon seemed weird, and then I realized it was actually awesome. Tzatziki is one of my favorite dipping sauces and using that as the ‘sticky’ layer under the breadcrumbs would give the salmon a great hit of flavor. And having the recipe all set up for lunches makes it even better. I love having leftovers for lunch. Cook once, eat many times. :)
Dana says
How on earth have I never, ever thought to slather tzatziki over salmon? As a lover of both, I feel like I have seriously failed myself. Ha. Needless to say, I’m all over this recipe, Carmy. It’s such a fun and easy dinner idea, and would go with pretty much any side! Or over a bountiful salad!